Non-communicable disease risk and HIV in rural South Africa

Project title
Non-communicable disease risk and HIV in rural South Africa

Research question
Non-communicable disease risk and HIV in rural South Africa

Rationale
The HIV epidemic in sub-Saharan Africa is increasingly being accompanied by a new emerging epidemic of non-communicable disease, particularly cardiovascular diseases. The scale-up of antiretroviral therapy and declining mortality due to improved survival of people wit HIV/AIDS suggests an increased burden of cardio-metabolic diseases and associated risk factors. The growing need for chronic care of both HIV/AIDS and and cardio-metabolic diseases, in South Africa and regionally, highlights the importance of greater understanding the burden and risk factors of these diseases. Using a cross-sectional survey the association of cardio-metabolic risk factors with HIV-status and use of ART is investigated in more than 4 500 men and women from 15 to 80 years of age. The survey is conducted in the Agincourt Health and Socio-Demographic Surveillance System located in rural northeast South Africa, close to the Mozambiquan border.

Investigators 
S. Tollman, J. Menken, K. Klipstein-Grobusch, J.Williams, F.X. Gómez-Olivé, N. Angotti, B. Houle, C. Kabudula, S. Clark Timeframe: 2010-2013 Partners: School of Public Health, University of the Witwatersrand, Johannesburg, South Africa; MRC / WITS Rural Public Health and Health Transitions Research Unit, Johannesburg, South Africa;
University of Colorado, Boulders, USA;
University of Washington, Seattle, USA Funding: National Institute of Aging (USA);
National Institutes of Health (USA); Wellcome Trust (UK);
William and Flora Hewlett Foundation (USA);
Anglo American Chairman’s Fund (South Africa)